This observation is intriguing for 2 other good reasons. 1st, it suggests that cells can take up MIF by ENDOCYTOSIS. offered the ample intracellular expression of MIF, it would be asked what advantage would the mobile acquire through the use of endocytosed MIF as an alternative to intracellular MIF. Endocytosis of MIF may possibly happen either wit
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One of the initial reviews on the MIF’s involvement in AD determined MIF as a different Aβ-binding protein inside of a soluble portion of the cerebral cortex of AD Mind by immunoprecipitation [seventy three, seventy four]. Some early experiences making use of immunohistochemistry reported elevated expression of CD74, a MIF receptor in advert [se